Effects of Metamizole, 4-Methylaminoantipyrine, and 4-Aminoantipyrine on LX-2 Liver Cell Line Viability and Apoptosis

Effects of Metamizole, 4-Methylaminoantipyrine, and 4-Aminoantipyrine on LX-2 Liver Cell Line Viability and Apoptosis

Metamizole (dipyrone) is a non-opioid analgesic widely used in human and veterinary medicine, despite ongoing concerns about its safety due to risks such as agranulocytosis and potential hepatotoxicity. This study investigates the cytotoxic (MTT assay) and pro-apoptotic effects of metamizole and its...

Full description

Saved in:
Bibliographic Details
Main Authors: Georgiana-Iulia Lupu, Emoke Pall, Mihai Cenariu, Monica Irina Nan, Sanda Andrei
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
metamizole
metabolites
hepatotoxicity
liver cell lines
Online Access:https://www.mdpi.com/1420-3049/30/1/17
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/1420-3049/30/1/17

Similar Items