Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD), including its more severe manifestation metabolic dysfunction‐associated steatohepatitis (MASH), poses global public health threats with limited therapeutics. Here, the role of alnustone is explored, a natural compound derive...

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Main Authors: Shourui Hu, Xiaofan Liang, Yiming Qin, Yuxuan Li, Yue Liu, Congcong Liu, Zongxuan Lin, Chunxuan Geng, Yanqi Xu, Daimin Wei, Yingying Qin, Han Zhao, Yuqing Zhang, Zi‐Jiang Chen
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Advanced Science
Subjects:
alnustone
calmodulin
fatty acid β‐oxidation
metabolic dysfunction‐associated steatohepatitis
metabolic dysfunction‐associated steatotic liver disease
Online Access:https://doi.org/10.1002/advs.202411984
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https://doi.org/10.1002/advs.202411984

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