PLUNC downregulates the expression of PD-L1 by inhibiting the interaction of DDX17/β-catenin in nasopharyngeal carcinoma

PLUNC downregulates the expression of PD-L1 by inhibiting the interaction of DDX17/β-catenin in nasopharyngeal carcinoma

Background Nasopharyngeal carcinoma (NPC) is characterized by high programmed death-ligand 1 (PD-L1) expression and abundant infiltration of non-malignant lymphocytes, which renders patients potentially suitable candidates for immune checkpoint blockade therapies. Palate, lung, and nasal epithelium...

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Bibliographic Details
Main Authors: Ranran Feng, Yilin Guo, Meilin Chen, Ziying Tian, Yijun Liu, Su Jiang, Jieyu Zhou, Qingluan Liu, Xiayu Li, Wei Xiong, Lei Shi, Songqing Fan, Guiyuan Li, Wenling Zhang
Format: Article
Language:English
Published: Korean Society of Pathologists & the Korean Society for Cytopathology 2025-01-01
Series:Journal of Pathology and Translational Medicine
Subjects:
bpifa1 protein
dead-box rna helicases 17
programmed cell death 1 ligand 1
Online Access:http://www.jpatholtm.org/upload/pdf/jptm-2024-11-27.pdf
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http://www.jpatholtm.org/upload/pdf/jptm-2024-11-27.pdf

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