Dexamethasone: a double-edged sword in the treatment of osteoarthritis

Dexamethasone: a double-edged sword in the treatment of osteoarthritis

Abstract Glucocorticoids are widely used to manage osteoarthritis (OA) symptoms, but long-term safety concerns exist. This study investigates the therapeutic potential of dexamethasone (DEX) and triamcinolone acetonide (TA) in chondrocytes, evaluating their anti-inflammatory effects and potential de...

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Bibliographic Details
Main Authors: Karyna Tarasova, Maria Belen Arteaga, Angkana Kidtiwong, Sinan Gueltekin, Andrea Bileck, Christopher Gerner, Iris Gerner, Florien Jenner
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Osteoarthritis
Glucocorticoids
Triamcinolone
Dexamethasone
Senescence
Apoptosis
Online Access:https://doi.org/10.1038/s41598-025-96050-2
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https://doi.org/10.1038/s41598-025-96050-2

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