Alpha-1 Antitrypsin Deficiency Targeted Testing and Augmentation Therapy: A Canadian Thoracic Society Clinical Practice Guideline

Alpha-1 Antitrypsin Deficiency Targeted Testing and Augmentation Therapy: A Canadian Thoracic Society Clinical Practice Guideline

Alpha-1 antitrypsin (A1AT) functions primarily to inhibit neutrophil elastase, and deficiency predisposes individuals to the development of chronic obstructive pulmonary disease (COPD). Severe A1AT deficiency occurs in one in 5000 to one in 5500 of the North American population. While the exact prev...

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Main Authors: DD Marciniuk, P Hernandez, M Balter, J Bourbeau, KR Chapman, GT Ford, JL Lauzon, F Maltais, DE O’Donnell, D Goodridge, C Strange, AJ Cave, K Curren, S Muthuri, Canadian Thoracic Society COPD Clinical Assembly Alpha-1 Antitrypsin Deficiency Expert Working Group
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2012/920918
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http://dx.doi.org/10.1155/2012/920918

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