Non-linear hierarchy of the quorum sensing signalling pathway in bloodstream form African trypanosomes.

Trypanosoma brucei, the agents of African trypanosomiasis, undergo density-dependent differentiation in the mammalian bloodstream to prepare for transmission by tsetse flies. This involves the generation of cell-cycle arrested, quiescent, stumpy forms from proliferative slender forms. The signalling...

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Bibliographic Details
Main Authors: Lindsay McDonald, Mathieu Cayla, Alasdair Ivens, Binny M Mony, Paula MacGregor, Eleanor Silvester, Kirsty McWilliam, Keith R Matthews
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-06-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1007145&type=printable
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