Contribution of Rare and Common <i>APOE</i> Variants to Familial Hypercholesterolemia in Spanish Cohort

Contribution of Rare and Common <i>APOE</i> Variants to Familial Hypercholesterolemia in Spanish Cohort

Our aim was to determine whether rare <i>APOE</i> pathogenic variants (PV) and the common e2/e3/e4 polymorphism were associated with the risk of familial hypercholesterolemia (FH). A total of 431 patients who met the inclusion criteria for FH were next-generation sequenced for the main c...

Full description

Saved in:
Bibliographic Details
Main Authors: Lorena M. Vega-Prado, Daniel Vázquez-Coto, Francisco Villazón, Lorena Suárez-Gutiérrez, Ceferino Martínez-Faedo, Edelmiro Menéndez-Torre, María Riestra, Silvia González-Martínez, Gala Gutiérrez-Buey, Claudia García-Lago, Juan Gómez, Victoria Alvarez, Helena Gil, Rebeca Lorca, Eliecer Coto
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Cardiogenetics
Subjects:
familial hypercholesterolemia
apolipoprotein E
polymorphisms
genetic association
Online Access:https://www.mdpi.com/2035-8148/15/1/3
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.mdpi.com/2035-8148/15/1/3

Similar Items