SID-2 is a conserved extracellular vesicle protein that is not associated with environmental RNAi in parasitic nematodes

SID-2 is a conserved extracellular vesicle protein that is not associated with environmental RNAi in parasitic nematodes

In the free-living nematode Caenorhabditis elegans, the transmembrane protein SID-2 imports double-stranded RNA into intestinal cells to trigger systemic RNA interference (RNAi), allowing organisms to sense and respond to environmental cues such as the presence of pathogens. This process, known as e...

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Bibliographic Details
Main Authors: Frances Blow, Kate Jeffrey, Franklin Wang-Ngai Chow, Inna A. Nikonorova, Maureen M. Barr, Atlanta G. Cook, Bram Prevo, Dhanya K. Cheerambathur, Amy H. Buck
Format: Article
Language:English
Published: The Royal Society 2024-11-01
Series:Open Biology
Subjects:
extracellular vesicles
membrane protein
environmental RNAi
nematodes
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.240190
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