Identifying insertion mutations by whole-genome sequencing

Insertion mutagenesis via mobile genetic element is a common technique for the analysis of gene function in model organisms. Next-generation sequencing offers an attractive approach for localizing the site of insertion, but alignment-based mapping of mobile genetic elements is challenging. A computa...

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Bibliographic Details
Main Author: Harold E. Smith
Format: Article
Language:English
Published: Taylor & Francis Group 2011-02-01
Series:BioTechniques
Subjects:
Online Access:https://www.future-science.com/doi/10.2144/000113600
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