Generative and Contrastive Self-Supervised Learning for Virulence Factor Identification Based on Protein–Protein Interaction Networks

Virulence factors (VFs), produced by pathogens, facilitate pathogenic microorganisms to invade, colonize, and damage the host cells. Accurate VF identification advances pathogenic mechanism understanding and provides novel anti-virulence targets. Existing models primarily utilize protein sequence fe...

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Bibliographic Details
Main Authors: Yalin Yao, Hao Chen, Jianxin Wang, Yeru Wang
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Microorganisms
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Online Access:https://www.mdpi.com/2076-2607/13/7/1635
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