Implications of Therapy-Induced Selective Autophagy on Tumor Metabolism and Survival

Accumulating evidence indicates that therapies designed to trigger apoptosis in tumor cells cause mitochondrial depolarization, nuclear damage, and the accumulation of misfolded protein aggregates, resulting in the activation of selective forms of autophagy. These selective forms of autophagy, inclu...

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Bibliographic Details
Main Authors: Luke R. K. Hughson, Vincent I. Poon, Jaeline E. Spowart, Julian J. Lum
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:International Journal of Cell Biology
Online Access:http://dx.doi.org/10.1155/2012/872091
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