IMMUNOBIOLOGICAL PROPERTIES OF FOWLPOX VIRUS CULTURAL VARIANTS

The paper presents experimental data of immunobiological properties of fowl pox virus cultural variants adapted in «F» CEF primary culture and «D» chicken embryo dermal primary cell culture. It was established that the strains retain dermatotropic phenotype manifested as local skin lesions in chicks...

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Main Authors: K. Yu. Fedoseyev, M. S. Kukushkina, V. Yu. Kulakov, L. V. Malakhova
Format: Article
Language:English
Published: Da Vinci Media 2018-04-01
Series:Ветеринария сегодня
Subjects:
Online Access:https://veterinary.arriah.ru/jour/article/view/216
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author K. Yu. Fedoseyev
M. S. Kukushkina
V. Yu. Kulakov
L. V. Malakhova
author_facet K. Yu. Fedoseyev
M. S. Kukushkina
V. Yu. Kulakov
L. V. Malakhova
author_sort K. Yu. Fedoseyev
collection DOAJ
description The paper presents experimental data of immunobiological properties of fowl pox virus cultural variants adapted in «F» CEF primary culture and «D» chicken embryo dermal primary cell culture. It was established that the strains retain dermatotropic phenotype manifested as local skin lesions in chicks, typical for Avipoxvirus family. They are also immunogenic and that is demonstrated as a protection after the vaccination with a homologous virus. The immunization doses were determined for both studied virus variants which ensured 95% protection of vaccinated birds. The doses were 14,6 и 6,97 ID50 for «F» and «D» correspondingly.
format Article
id doaj-art-180170ecabae41c6aa41ad8710cbf2b6
institution Kabale University
issn 2304-196X
2658-6959
language English
publishDate 2018-04-01
publisher Da Vinci Media
record_format Article
series Ветеринария сегодня
spelling doaj-art-180170ecabae41c6aa41ad8710cbf2b62025-02-06T09:52:05ZengDa Vinci MediaВетеринария сегодня2304-196X2658-69592018-04-01042934216IMMUNOBIOLOGICAL PROPERTIES OF FOWLPOX VIRUS CULTURAL VARIANTSK. Yu. Fedoseyev0M. S. Kukushkina1V. Yu. Kulakov2L. V. Malakhova3FGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirFGBI "ARRIAH", VladimirThe paper presents experimental data of immunobiological properties of fowl pox virus cultural variants adapted in «F» CEF primary culture and «D» chicken embryo dermal primary cell culture. It was established that the strains retain dermatotropic phenotype manifested as local skin lesions in chicks, typical for Avipoxvirus family. They are also immunogenic and that is demonstrated as a protection after the vaccination with a homologous virus. The immunization doses were determined for both studied virus variants which ensured 95% protection of vaccinated birds. The doses were 14,6 и 6,97 ID50 for «F» and «D» correspondingly.https://veterinary.arriah.ru/jour/article/view/216вирус оспы птицкультивированиеинфекционная активностьfowl pox viruscultureinfectivity
spellingShingle K. Yu. Fedoseyev
M. S. Kukushkina
V. Yu. Kulakov
L. V. Malakhova
IMMUNOBIOLOGICAL PROPERTIES OF FOWLPOX VIRUS CULTURAL VARIANTS
Ветеринария сегодня
вирус оспы птиц
культивирование
инфекционная активность
fowl pox virus
culture
infectivity
title IMMUNOBIOLOGICAL PROPERTIES OF FOWLPOX VIRUS CULTURAL VARIANTS
title_full IMMUNOBIOLOGICAL PROPERTIES OF FOWLPOX VIRUS CULTURAL VARIANTS
title_fullStr IMMUNOBIOLOGICAL PROPERTIES OF FOWLPOX VIRUS CULTURAL VARIANTS
title_full_unstemmed IMMUNOBIOLOGICAL PROPERTIES OF FOWLPOX VIRUS CULTURAL VARIANTS
title_short IMMUNOBIOLOGICAL PROPERTIES OF FOWLPOX VIRUS CULTURAL VARIANTS
title_sort immunobiological properties of fowlpox virus cultural variants
topic вирус оспы птиц
культивирование
инфекционная активность
fowl pox virus
culture
infectivity
url https://veterinary.arriah.ru/jour/article/view/216
work_keys_str_mv AT kyufedoseyev immunobiologicalpropertiesoffowlpoxvirusculturalvariants
AT mskukushkina immunobiologicalpropertiesoffowlpoxvirusculturalvariants
AT vyukulakov immunobiologicalpropertiesoffowlpoxvirusculturalvariants
AT lvmalakhova immunobiologicalpropertiesoffowlpoxvirusculturalvariants