Fibro-adipogenic progenitor cells in skeletal muscle unloading: metabolic and functional impairments

Fibro-adipogenic progenitor cells in skeletal muscle unloading: metabolic and functional impairments

Abstract Background Skeletal muscle resident fibro-adipogenic progenitor cells (FAPs) control skeletal muscle regeneration providing a supportive role for muscle stem cells. Altered FAPs characteristics have been shown for a number of pathological conditions, but the influence of temporary functiona...

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Main Authors: Margarita Sorokina, Danila Bobkov, Natalia Khromova, Natalia Vilchinskaya, Boris Shenkman, Anna Kostareva, Renata Dmitrieva
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Skeletal Muscle
Subjects:
Soleus muscle
Functional unloading
Fibro-adipogenic progenitors (FAPs)
C2C12 myoblasts
Skeletal muscle regeneration
Adipogenic differentiation
Online Access:https://doi.org/10.1186/s13395-024-00362-2
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https://doi.org/10.1186/s13395-024-00362-2

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