Synthesis of Diversely Substituted Diethyl (Pyrrolidin-2-Yl)Phosphonates

Synthesis of Diversely Substituted Diethyl (Pyrrolidin-2-Yl)Phosphonates

Imidazoline I<sub>2</sub> receptors (I<sub>2</sub>-IR) are untapped therapeutic targets lacking a structural description. Although the levels of I<sub>2</sub>-IR are dysregulated in a plethora of illnesses, the arsenal of ligands that can modulate I<sub>2<...

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Bibliographic Details
Main Authors: Andrea Bagán, Alba López-Ruiz, Sònia Abás, Elies Molins, Belén Pérez, Itziar Muneta-Arrate, Luis F. Callado, Carmen Escolano
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Molecules
Subjects:
α-aminophosphonate
pyrroline
phosphonic ester
(pyrrolidine-2-yl)phosphonate
phosphoproline
imidazoline I<sub>2</sub> receptor ligand
Online Access:https://www.mdpi.com/1420-3049/30/9/2078
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