Probiotics ameliorate H. pylori-associated gastric β-catenin and COX-2 carcinogenesis signaling by regulating miR-185

Probiotics ameliorate H. pylori-associated gastric β-catenin and COX-2 carcinogenesis signaling by regulating miR-185

Abstract Background This study aimed to investigate whether probiotics can ameliorate the H. pylori-induced Wnt/β-catenin-related COX-2 carcinogenesis signaling pathway by regulating the expression of microRNAs (miRNAs). Methods An H. pylori isolate and GES-1 cells were used to establish a COX-2-ass...

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Bibliographic Details
Main Authors: Yao-Jong Yang, Chung-Tai Wu, Hsiu-Chi Cheng, Wei-Ying Chen, Joseph T. Tseng, Wei-Lun Chang, Bor-Shyang Sheu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Biomedical Science
Subjects:
Probiotics
MiR-185
H. pylori
Carcinogenesis
COX-2
Wnt/β-catenin
Online Access:https://doi.org/10.1186/s12929-025-01149-3
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https://doi.org/10.1186/s12929-025-01149-3

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