Clinical advances in antibody-drug conjugates for hematological malignancies

An antibody-drug conjugate (ADC) is a targeted therapeutic drug composed of a monoclonal antibody linked to a small-molecule cytotoxic drug via a linker. Once administered, ADCs bind to tumor-specific antigens, forming ADC-antigen complexes, which are internalized through endocytosis. The linkers ar...

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Bibliographic Details
Main Authors: TANG Sijie, MI Jianqing
Format: Article
Language:zho
Published: Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science) 2024-12-01
Series:Shanghai Jiaotong Daxue xuebao. Yixue ban
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Online Access:https://xuebao.shsmu.edu.cn/article/2024/1674-8115/1674-8115-2024-44-12-1607.shtml
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