Clinical advances in antibody-drug conjugates for hematological malignancies
An antibody-drug conjugate (ADC) is a targeted therapeutic drug composed of a monoclonal antibody linked to a small-molecule cytotoxic drug via a linker. Once administered, ADCs bind to tumor-specific antigens, forming ADC-antigen complexes, which are internalized through endocytosis. The linkers ar...
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Main Authors: | , |
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Format: | Article |
Language: | zho |
Published: |
Editorial Office of Journal of Shanghai Jiao Tong University (Medical Science)
2024-12-01
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Series: | Shanghai Jiaotong Daxue xuebao. Yixue ban |
Subjects: | |
Online Access: | https://xuebao.shsmu.edu.cn/article/2024/1674-8115/1674-8115-2024-44-12-1607.shtml |
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