GSR Deficiency Exacerbates Oxidative Stress and Promotes Pulmonary Fibrosis

GSR Deficiency Exacerbates Oxidative Stress and Promotes Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disorder characterized by excessive scarring of lung tissue, predominantly affecting middle-aged and elderly populations. Oxidative stress plays a pivotal role in the pathogenesis of pulmonary fibrosis, disrupting redox homeostasis...

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Bibliographic Details
Main Authors: Wenyu Zhao, Hehe Cao, Wenbo Xu, Yudi Duan, Yulong Gan, Shuang Huang, Ying Cao, Siqi Long, Yingying Zhang, Guoying Yu, Lan Wang
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomolecules
Subjects:
idiopathic pulmonary fibrosis
type II alveolar epithelial cell
fibroblast
GSR
oxidative stress
ROS
Online Access:https://www.mdpi.com/2218-273X/15/7/1050
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