The fatty acid synthesis gene fabY affects lipopolysaccharide synthesis and colistin susceptibility in Pseudomonas aeruginosa
ABSTRACT Bacterial metabolism impacts susceptibility to antibiotics. Here, we found that mutation of the Pseudomonas aeruginosa fatty acid response regulator gene pvrA decreases bacterial susceptibility to colistin. The fatty acid synthesis gene fabY is upregulated in the pvrA mutant. Deletion of fa...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2025-08-01
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| Series: | Microbiology Spectrum |
| Subjects: | |
| Online Access: | https://journals.asm.org/doi/10.1128/spectrum.01339-25 |
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