Selection of DNA Aptamers for Ovarian Cancer Biomarker CA125 Using One-Pot SELEX and High-Throughput Sequencing

CA125 is a mucin glycoprotein whose concentration in serum correlates with a woman’s risk of developing ovarian cancer and also indicates response to therapy in diagnosed patients. Accurate detection of this large, complex protein in patient samples is of great clinical relevance. We suggest that po...

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Bibliographic Details
Main Authors: Delia J. Scoville, Tae Kyu Brian Uhm, Jamie A. Shallcross, Rebecca J. Whelan
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.1155/2017/9879135
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