miR-144-3p targeting FLRT3 in osteogenic differentiation of mandibular bone marrow mesenchymal stem cells

miR-144-3p targeting FLRT3 in osteogenic differentiation of mandibular bone marrow mesenchymal stem cells

Abstract Background Fibronectin Leucine-Rich Transmembrane Protein 3 (FLRT3) plays a crucial role in craniofacial development and osteogenic differentiation, yet the regulatory mechanisms of microRNAs (miRNAs) on FLRT3 remain largely unexplored. This study identifies miR-144-3p as a miRNA that targe...

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Bibliographic Details
Main Authors: Jingjun Tian, Chen Lv, Tao Xie, Qi Sun, Changyu Liu, Wen Ma, Chaofeng Liu, Renyi Cheng, Kang Yin, Yanhua Xu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Human Genomics
Subjects:
Fibronectin leucine-rich transmembrane protein 3
Mandibular bone marrow mesenchymal stem cells
miR-144-3p
Osteogenic differentiation
Online Access:https://doi.org/10.1186/s40246-025-00788-9
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https://doi.org/10.1186/s40246-025-00788-9

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