Restoration of retinal regenerative potential of Müller glia by disrupting intercellular Prox1 transfer

Restoration of retinal regenerative potential of Müller glia by disrupting intercellular Prox1 transfer

Abstract Individuals with retinal degenerative diseases struggle to restore vision due to the inability to regenerate retinal cells. Unlike cold-blooded vertebrates, mammals lack Müller glia (MG)-mediated retinal regeneration, indicating the limited regenerative capacity of mammalian MG. Here, we id...

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Main Authors: Eun Jung Lee, Museong Kim, Sooyeon Park, Ji Hyeon Shim, Hyun-Ju Cho, Jung Ah Park, Kihyun Park, Dongeun Lee, Jeong Hwan Kim, Haeun Jeong, Fumio Matsuzaki, Seon-Young Kim, Jaehoon Kim, Hanseul Yang, Jeong-Soo Lee, Jin Woo Kim
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58290-8
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https://doi.org/10.1038/s41467-025-58290-8

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