Low LDL-cholesterol drives the risk of bleeding in patients treated with aspirin: A 15-year study in a real-world large population

Low LDL-cholesterol drives the risk of bleeding in patients treated with aspirin: A 15-year study in a real-world large population

We aimed to investigate the link between LDL cholesterol (LDL-C) levels and hemorrhage risk over an extended period, both in subjects taking aspirin and in individuals not receiving any antiplatelet agent. We calculated the predicted adjusted relative hazard of bleeding by LDL-C concentration for th...

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Main Authors: Valentina Trimarco, Raffaele Izzo, Daniela Pacella, Fahimeh Varzideh, Maria Virginia Manzi, Paola Gallo, Giuseppe Giugliano, Roberto Piccinocchi, Giovanni Esposito, Gaetano Piccinocchi, Luca Bardi, Carmine Morisco, Francesco Rozza, Maria Lembo, Bruno Trimarco, Gaetano Santulli
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Pharmacological Research
Subjects:
Aspirin
Bleeding
Cholesterol
Dyslipidemia
Hemorrhage
LDL
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661825001136
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