Effects of vagus nerve stimulation on daily function and quality of life in markedly treatment-resistant major depression: Findings from a one-year, randomized, sham-controlled trial

Effects of vagus nerve stimulation on daily function and quality of life in markedly treatment-resistant major depression: Findings from a one-year, randomized, sham-controlled trial

Background: Depression treatments aim to minimize symptom burden and optimize quality of life (QoL) and psychosocial function. Objective: Compare the effects of adjunctive versus sham vagus nerve stimulation (VNS) on QoL and function in markedly treatment-resistant depression (TRD). Methods: In this...

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Main Authors: A. John Rush, Charles R. Conway, Scott T. Aaronson, Mark S. George, Patricio Riva-Posse, David L. Dunner, John Zajecka, Mark T. Bunker, João Quevedo, Rebecca M. Allen, Gustavo Alva, Heather Luing, Ziad Nahas, Lucian Manu, Jeffrey I. Bennett, Brian J. Mickey, Jonathan Becker, Yvette Sheline, Cristina Cusin, James W. Murrough, Kevin Reeves, Peter B. Rosenquist, Ying-Chieh (Lisa) Lee, Shannon Majewski, Jeffrey Way, Bryan Olin, Harold A. Sackeim
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Brain Stimulation
Subjects:
Treatment-resistant depression
Vagus nerve stimulation
RECOVER trial
Quality of life
Function
Efficacy
Online Access:http://www.sciencedirect.com/science/article/pii/S1935861X24013822
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