Lyophilized B. subtilis ZB183 Spores: 90-Day Repeat Dose Oral (Gavage) Toxicity Study in Wistar Rats

A 90-day repeated-dose oral toxicological evaluation was conducted according to GLP and OECD guidelines on lyophilized spores of the novel genetically modified strain B. subtilis ZB183. Lyophilized spores at doses of 109, 1010, and 1011 CFU/kg body weight/day were administered by oral gavage to Wist...

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Bibliographic Details
Main Authors: B. Appala Naidu, Kamala Kannan, D. P. Santhosh Kumar, John W. K. Oliver, Zachary D. Abbott
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2019/3042108
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