Safety and immunogenicity of an AMA-1 malaria vaccine in Malian adults: results of a phase 1 randomized controlled trial.

Safety and immunogenicity of an AMA-1 malaria vaccine in Malian adults: results of a phase 1 randomized controlled trial.

<h4>Background</h4>The objective was to evaluate the safety, reactogenicity and immunogenicity of the AMA-1-based blood-stage malaria vaccine FMP2.1/AS02A in adults exposed to seasonal malaria.<h4>Methodology/principal findings</h4>A phase 1 double blind randomized controlled...

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Main Authors: Mahamadou A Thera, Ogobara K Doumbo, Drissa Coulibaly, Dapa A Diallo, Abdoulaye K Kone, Ando B Guindo, Karim Traore, Alassane Dicko, Issaka Sagara, Mahamadou S Sissoko, Mounirou Baby, Mady Sissoko, Issa Diarra, Amadou Niangaly, Amagana Dolo, Modibo Daou, Sory I Diawara, D Gray Heppner, V Ann Stewart, Evelina Angov, Elke S Bergmann-Leitner, David E Lanar, Sheetij Dutta, Lorraine Soisson, Carter L Diggs, Amanda Leach, Alex Owusu, Marie-Claude Dubois, Joe Cohen, Jason N Nixon, Aric Gregson, Shannon L Takala, Kirsten E Lyke, Christopher V Plowe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0001465&type=printable
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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0001465&type=printable

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