Mitotically Active Plexiform Fibrohistiocytic Tumor
Plexiform fibrohistiocytic tumor is an intermediate malignant tumor situated in superficial soft tissues. It affects children and young adults. The tumor is most commonly located on upper extremities, whereas involvement of back region is rare. Mitotic activity is generally low (~3/10 HPF). It is ra...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2013/547372 |
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| author | Ebru Zemheri Şeyma Özkanlı Serkan Şenol Filiz Ozen Cigdem Ulukaya Durakbaşa İlkin Zindancı Hamit Okur |
| author_facet | Ebru Zemheri Şeyma Özkanlı Serkan Şenol Filiz Ozen Cigdem Ulukaya Durakbaşa İlkin Zindancı Hamit Okur |
| author_sort | Ebru Zemheri |
| collection | DOAJ |
| description | Plexiform fibrohistiocytic tumor is an intermediate malignant tumor situated in superficial soft tissues. It affects children and young adults. The tumor is most commonly located on upper extremities, whereas involvement of back region is rare. Mitotic activity is generally low (~3/10 HPF). It is rare, but it can exhibit aggressive behavior, so total excision with clear surgical margins and long-term followup is necessary to detect local recurrence and metastases. We report a child with a solid mass on back region which was found to be a mitotically active plexiform fibrohistiocytic tumor (6/10 HPF) after excision.
Plexiform fibrohistiocytic tumor (PFT) is a mesenchymal neoplasm of children, adolescents, and young adults. It is characterized by fibrohistiocytic cytomorphology and multinodular growth pattern. Clinically it is usually a slow-growing mass of upper extremities with frequent local recurrence and rare regional lymphatic and systemic metastasis (Fletcher et al. (2002), Enzinger and Zhang (1988), Remstein et al. (1999)). |
| format | Article |
| id | doaj-art-158b3f5c832b4a87a62edf93979b2331 |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-158b3f5c832b4a87a62edf93979b23312025-02-03T05:57:34ZengWileyCase Reports in Pathology2090-67812090-679X2013-01-01201310.1155/2013/547372547372Mitotically Active Plexiform Fibrohistiocytic TumorEbru Zemheri0Şeyma Özkanlı1Serkan Şenol2Filiz Ozen3Cigdem Ulukaya Durakbaşa4İlkin Zindancı5Hamit Okur6Department of Pathology, Istanbul Medeniyet University Goztepe Training and Research Hospital, TurkeyDepartment of Pathology, Istanbul Medeniyet University Goztepe Training and Research Hospital, TurkeyDepartment of Pathology, Istanbul Medeniyet University Goztepe Training and Research Hospital, TurkeyDepartment of Medıcal Genetics, Istanbul Medeniyet University Goztepe Training and Research Hospital, TurkeyDepartment of Pediatric Surgery, Istanbul Medeniyet University Goztepe Training and Research Hospital, TurkeyDepartment of Dermatology, Istanbul Medeniyet University Goztepe Training and Research Hospital, TurkeyDepartment of Pediatric Surgery, Istanbul Medeniyet University Goztepe Training and Research Hospital, TurkeyPlexiform fibrohistiocytic tumor is an intermediate malignant tumor situated in superficial soft tissues. It affects children and young adults. The tumor is most commonly located on upper extremities, whereas involvement of back region is rare. Mitotic activity is generally low (~3/10 HPF). It is rare, but it can exhibit aggressive behavior, so total excision with clear surgical margins and long-term followup is necessary to detect local recurrence and metastases. We report a child with a solid mass on back region which was found to be a mitotically active plexiform fibrohistiocytic tumor (6/10 HPF) after excision. Plexiform fibrohistiocytic tumor (PFT) is a mesenchymal neoplasm of children, adolescents, and young adults. It is characterized by fibrohistiocytic cytomorphology and multinodular growth pattern. Clinically it is usually a slow-growing mass of upper extremities with frequent local recurrence and rare regional lymphatic and systemic metastasis (Fletcher et al. (2002), Enzinger and Zhang (1988), Remstein et al. (1999)).http://dx.doi.org/10.1155/2013/547372 |
| spellingShingle | Ebru Zemheri Şeyma Özkanlı Serkan Şenol Filiz Ozen Cigdem Ulukaya Durakbaşa İlkin Zindancı Hamit Okur Mitotically Active Plexiform Fibrohistiocytic Tumor Case Reports in Pathology |
| title | Mitotically Active Plexiform Fibrohistiocytic Tumor |
| title_full | Mitotically Active Plexiform Fibrohistiocytic Tumor |
| title_fullStr | Mitotically Active Plexiform Fibrohistiocytic Tumor |
| title_full_unstemmed | Mitotically Active Plexiform Fibrohistiocytic Tumor |
| title_short | Mitotically Active Plexiform Fibrohistiocytic Tumor |
| title_sort | mitotically active plexiform fibrohistiocytic tumor |
| url | http://dx.doi.org/10.1155/2013/547372 |
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