Clinical characteristics of patients with cerebellar ataxia associated with anti-GAD antibodies

Clinical characteristics of patients with cerebellar ataxia associated with anti-GAD antibodies

ABSTRACT The enzyme glutamic acid decarboxylase (GAD), present in GABAergic neurons and in pancreatic beta cells, catalyzes the conversion of gamma-aminobutyric acid (GABA). The cerebellum is highly susceptible to immune-mediated mechanisms, with the potentially treatable autoimmune cerebellar ataxi...

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Main Authors: Tiago Silva Aguiar, Andrea Fragoso, Carolina Rouanet de Albuquerque, Patrícia de Fátima Teixeira, Marcus Vinícius Leitão de Souza, Lenita Zajdenverg, Soniza Vieira Alves-Leon, Melanie Rodacki, Marco Antônio Sales Dantas de Lima
Format: Article
Language:English
Published: Thieme Revinter Publicações
Series:Arquivos de Neuro-Psiquiatria
Subjects:
autoimmunity
cerebellar ataxia
diabetes mellitus
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000300142&lng=en&tlng=en
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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000300142&lng=en&tlng=en

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