Prevalence of Rheumatic Heart Disease in First-degree Relatives of Index-cases: A Systematic Review and Meta-Analysis

Prevalence of Rheumatic Heart Disease in First-degree Relatives of Index-cases: A Systematic Review and Meta-Analysis

Background: Rheumatic heart disease (RHD) is the leading cause of cardiac death in children, with over 300,000 annual fatalities. Immunological, genetic, and environmental factors contribute to an increased risk of RHD. It remains unclear whether first-degree relatives have a higher RHD prevalence t...

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Main Authors: Antonio Mutarelli, Guilherme Paes Gonçalves Nogueira, Alexandre Negrao Pantaleao, Alleh Nogueira, Bruna Giavina-Bianchi, Isabella M. Gonzalez Fonseca, Bruno R. Nascimento, Walderez O. Dutra, Robert A. Levine, Maria C. P. Nunes, On behalf of PRIMA Network
Format: Article
Language:English
Published: Ubiquity Press 2025-03-01
Series:Global Heart
Subjects:
rheumatic heart disease
first-degree relative
family members
meta-analysis
Online Access:https://account.globalheartjournal.com/index.php/up-j-gh/article/view/1417
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