Bridging systemic metabolic dysfunction and Alzheimer’s disease: the liver interface

Abstract Alzheimer’s disease (AD) is increasingly recognized as a systemic disorder with a substantial metabolic disorder component, where the liver significantly impacts the brain via the liver-brain axis. Key mechanisms include the liver’s role in clearing peripheral β-amyloid (Aβ), the influence...

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Bibliographic Details
Main Authors: Dan Song, Yang Li, Ling-Ling Yang, Ya-Xi Luo, Xiu-Qing Yao
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Molecular Neurodegeneration
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Online Access:https://doi.org/10.1186/s13024-025-00849-6
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