Exploring the Anti-Osteoporotic Effects of <i>n</i>-Hexane Fraction from <i>Cotoneaster wilsonii</i> Nakai: Activation of Runx2 and Osteoblast Differentiation In Vivo

Exploring the Anti-Osteoporotic Effects of <i>n</i>-Hexane Fraction from <i>Cotoneaster wilsonii</i> Nakai: Activation of Runx2 and Osteoblast Differentiation In Vivo

Background: Osteoporosis is characterized by the microstructural depletion of bone tissue and decreased bone density, leading to an increased risk of fractures. <i>Cotoneaster wilsonii</i> Nakai, an endemic species of the Korean Peninsula, grows wild in Ulleungdo. In this study, we aimed...

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Bibliographic Details
Main Authors: Soyeon Hong, Hee Ju Lee, Da Seul Jung, Saruul Erdenebileg, Hoseong Hwang, Hak Cheol Kwon, Jaeyoung Kwon, Gyhye Yoo
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceuticals
Subjects:
<i>Cotoneaster wilsonii</i> Nakai
bone formation
osteoblast differentiation
osteoporosis
phytomedicine
ovariectomized mice
Online Access:https://www.mdpi.com/1424-8247/18/1/45
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