Enhanced efficacy of immune checkpoint inhibitors combined locoregional therapy and tyrosine kinase inhibitors in the treatment of unresectable hepatocellular carcinoma: A single - center retrospective study

Enhanced efficacy of immune checkpoint inhibitors combined locoregional therapy and tyrosine kinase inhibitors in the treatment of unresectable hepatocellular carcinoma: A single - center retrospective study

BackgroundUnresectable hepatocellular carcinoma (HCC) presents significant treatment challenges. While locoregional therapies (LT) and tyrosine kinase inhibitors (TKI) offer some benefits, prognosis remains poor. Immune checkpoint inhibitors (ICI) have shown promise in other oncological settings, su...

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Bibliographic Details
Main Authors: Junfeng Bu, Zihan Li, Die Hu, Ling Lan, Jiwei Huang, Xin Wang, Qiu Li, Jin Zhou, Yong Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Oncology
Subjects:
unresectable hepatocellular carcinoma
locoregional therapy
tyrosine kinase inhibitor
immune checkpoint inhibitor
system therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1554711/full
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