Computational screening, synthesis and neuroprotective evaluation of small molecule for the treatment of alzheimer's disease

Computational screening, synthesis and neuroprotective evaluation of small molecule for the treatment of alzheimer's disease

BACKGROUND: Current treatments for Alzheimer’s disease primarily address symptoms, as no definitive therapeutic targets have been identified. OBJECTIVES: This study aims to conduct a virtual screening of small molecules and synthesize and evaluate one of the most promising candidates for Alzheimer...

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Bibliographic Details
Main Authors: Nerlis Pajaro-Castro, Elkin Torres-Sierra, Edwar Cortes-Gonzalez, Margaret Paternina, Erwin Camacho, Pedro Blanco
Format: Article
Language:English
Published: Universidad de Antioquia 2024-12-01
Series:Vitae
Subjects:
Alzheimer’s disease
Beta secretase
cyclin-dependent kinase 5
drug-like
gamma secretase
neurodegenerative
Online Access:https://revistas.udea.edu.co/index.php/vitae/article/view/354271
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https://revistas.udea.edu.co/index.php/vitae/article/view/354271

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