Enhanced cytotoxicity of aging associated NKG2C + CD8 + T cells in ankylosing spondylitis via HLA-B27

Abstract Background This study aims to explore the common mechanisms between aging and the pathogenesis of ankylosing spondylitis (AS) and to identify potential therapeutic targets. Methods A total of 87 patients with AS and matched controls were analyzed via multidimensional flow cytometry to exami...

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Bibliographic Details
Main Authors: Kunhai Tang, Xiaobei Ma, Jian Gao, Lilu Zu, Yanyun Ma, Dachun Zhuo, Chenyuan Wu, Yulong Tang, Feng Qian, Li Jin, Jiucun Wang, Qi Zhu, Jing Liu
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Arthritis Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13075-025-03585-w
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