General Phenotype of NADase Induction by CLI Treatment in Streptococcus pyogenes

The administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic-shock syndrome (STSS). However, we previously reported that a “subinhibitory dose” of CLI induced the expression of the NAD-glycohydrolase (NADase) exotoxin in an emm1-type...

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Bibliographic Details
Main Authors: Ichiro Tatsuno, Masanori Isaka, Tadao Hasegawa
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:International Journal of Microbiology
Online Access:http://dx.doi.org/10.1155/2022/4767765
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