STING modulates HBV-related acute-on-chronic liver failure by mediating autophagy and macrophage polarization

STING modulates HBV-related acute-on-chronic liver failure by mediating autophagy and macrophage polarization

Background & Aims: HBV-related acute-on-chronic liver failure (HBV-ACLF) is a severe acute liver injury secondary to HBV-related chronic liver disease (with or without cirrhosis) and is characterized by a high short-term mortality rate. Presently, there is a paucity of experimental models th...

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Main Authors: Hao Zhang, Teng Liang, Wanlu Duan, Futing Liu, LiPing Li, Qian Liu, Jianfei Li, Qiyin Zong, Lei Jin, Qin Wang, Qiang Zhou
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Immunobiology
Subjects:
HBV-related acute-on-chronic liver failure
Interferon gene stimulator protein
Autophagy
Online Access:http://www.sciencedirect.com/science/article/pii/S0171298524000780
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