IL-12 and Related Cytokines: Function and Regulatory Implications in Candida albicans Infection
IL-12 is a cytokine with links to both innate and adaptive immunity systems. In mice, its deletion leads to acute susceptibility to oral infection with the yeast Candida albicans, whereas such mice are resistant to systemic disease. However, it is an essential component of the adaptive response that...
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Main Authors: | Robert B. Ashman, Dipti Vijayan, Christine A. Wells |
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Format: | Article |
Language: | English |
Published: |
Wiley
2011-01-01
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Series: | Clinical and Developmental Immunology |
Online Access: | http://dx.doi.org/10.1155/2011/686597 |
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