Preparation of curcumin submicron particles by supercritical antisolvent method with external adjustable annular gap nozzle
Abstract The supercritical antisolvent (SAS) method can effectively improve the bioavailability of poorly water-soluble drugs. However, the current supercritical equipment and processes were not fully developed, making industrialization difficult to achieve. Therefore, an externally adjustable annul...
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Main Authors: | Yechen Wang, Zirui Li, Sun Fayu, Fei Li, Weiqiang Wang |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-025-87787-x |
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