Immune Dysregulation at the Maternal–Fetal Interface Exacerbates Adverse Pregnancy Outcomes in an Inflammatory Arthritis Murine Model

Immune Dysregulation at the Maternal–Fetal Interface Exacerbates Adverse Pregnancy Outcomes in an Inflammatory Arthritis Murine Model

<b>Objective<b>:</b></b> Inflammatory arthritis (IA) has been linked to a number of adverse pregnancy outcomes (APOs), but the mechanisms linking IA-related immune dysregulation to compromised reproductive success remain poorly understood. This project will examine how IA aff...

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Bibliographic Details
Main Authors: Chenxi Yang, Wenjuan Li, Xinxin Liu, Zijun Ma, Jun Chen, Quan Gong, Zachary Braunstein, Xiaoquan Rao, Yingying Wei, Jixin Zhong
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Biomedicines
Subjects:
inflammatory arthritis
pregnancy outcomes
SKG mice
T cells
inflammatory cytokines
Online Access:https://www.mdpi.com/2227-9059/13/6/1440
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