Myeloid-derived growth factor alleviates non-alcoholic fatty liver disease alleviates in a manner involving IKKβ/NF-κB signaling

Myeloid-derived growth factor alleviates non-alcoholic fatty liver disease alleviates in a manner involving IKKβ/NF-κB signaling

Abstract Whether bone marrow modulates systemic metabolism remains unknown. Our recent study suggested that myeloid-derived growth factor (MYDGF) improves insulin resistance. Here, we found that myeloid cell-specific MYDGF deficiency aggravated hepatic inflammation, lipogenesis, and steatosis, and s...

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Main Authors: Yan Ding, Xiaoli Xu, Biying Meng, Li Wang, Biao Zhu, Bei Guo, Jiajia Zhang, Lin Xiang, Jing Dong, Min Liu, Guangda Xiang
Format: Article
Language:English
Published: Nature Publishing Group 2023-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05904-y
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https://doi.org/10.1038/s41419-023-05904-y

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