Generation of vascularized pancreatic progenitors through co-differentiation of endoderm and mesoderm from human pluripotent stem cells

Generation of vascularized pancreatic progenitors through co-differentiation of endoderm and mesoderm from human pluripotent stem cells

Abstract Background The simultaneous differentiation of human pluripotent stem cells (hPSCs) into both endodermal and mesodermal lineages is crucial for developing complex, vascularized tissues, yet poses significant challenges. This study explores a method for co-differentiation of mesoderm and end...

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Bibliographic Details
Main Authors: Xiaopu Sang, Junming Xu, Yihang Wang, Jingyi Li, Jiasen Xu, Xiaoni Chen, Xianjie Shi, Fenfang Wu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Stem Cell Research & Therapy
Subjects:
Human pluripotent stem cells
Endoderm differentiation
Mesoderm differentiation
Multi-lineage co-differentiation
Vascularized pancreatic progenitors
Online Access:https://doi.org/10.1186/s13287-024-04120-5
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https://doi.org/10.1186/s13287-024-04120-5

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