Quantification of endogenous and therapeutic IgG crossing the kidney barrier from bloodstream to urine

This study investigates the biodistribution of a therapeutic antibody from serum to urine across the kidney endothelial barrier, contextualizing the findings with existing literature. Our analysis shows the quantitative correlation between serum levels of the intravenously administered antibody ritu...

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Bibliographic Details
Main Authors: Barbara Eicher, Christoph Esslinger, Matthias Hillenbrand
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1572739/full
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