Biotin interference in routine clinical immunoassays

Biotin interference in routine clinical immunoassays

Background: Laboratory examinations play a crucial role in medical diagnostics and treatment, necessitating the identification of interference factors to ensure accurate results. Biotin, a common dietary supplement, can interfere with immunoassays utilizing biotin-streptavidin interactions. Studies...

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Main Authors: Kuo-Chun Chiu, Jia-Rong Jhan, Hsiao-Ni Yan, Yu-Chen Liao, Wen-Hui Lu, Kuan-Yi Lee, Li-Yuan Cheng, Chung-Kang Yeh, Ya-Fen Lee, Chiung-Hui Kuo, Kuei-Pin Chung, Tzu-I Chien
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Practical Laboratory Medicine
Subjects:
Biotin tolerance
Immunoassay interference
Elecsys
Biotin depletion
Hemodialysis
ICU
Online Access:http://www.sciencedirect.com/science/article/pii/S2352551725000253
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