Recipient sex and donor leukemic cell characteristics determine leukemogenesis in patient-derived models

Recipient sex and donor leukemic cell characteristics determine leukemogenesis in patient-derived models

In acute myeloid leukemia (AML), leukemogenesis depends on cell-intrinsic genetic aberrations and thus, studies on AML require investigations in an in vivo setting as provided by patient derived xenografts (PDX) models. Here we report that, next to leukemic cell characteristics, recipient sex highl...

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Bibliographic Details
Main Authors: Anna MP. Stanger, Marlon Arnone, Pauline Hanns, Lucca M. Kimmich, Jessica Kübler, Sarah Gekeler, Elsa S. Görsch, Lea Kramer, Marcelle Baer, Jan C. Schroeder, Taylor S. Mills, Martina Konantz, Saskia S. Rudat, Claudia Lengerke
Format: Article
Language:English
Published: Ferrata Storti Foundation 2025-01-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/11892
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https://haematologica.org/article/view/11892

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