Pharmacophore-based approach for the identification of prospective UDP-2,3-diacylglucosamine hydrolase (LpxH) inhibitor from natural product database against Salmonella Typhi
Antibiotics are essential for the treatment of typhoid fever, which is caused by Salmonella Typhi. The global increase of antibiotic resistance in S. Typhi is a significant public health threat. The traditional approach to discovering new drugs is a lengthy process. To address this, ligand-based pha...
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Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-06-01
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Series: | Chemical Physics Impact |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S266702242500012X |
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