Expression profiles and bioinformatic analysis of circular RNA in rheumatic heart disease: potential hsa_circ_0001490 and hsa_circ_0001296 as a diagnostic biomarker

Expression profiles and bioinformatic analysis of circular RNA in rheumatic heart disease: potential hsa_circ_0001490 and hsa_circ_0001296 as a diagnostic biomarker

ObjectiveCircular RNAs (circRNAs) are involved in various Cardiovascular diseases; however, the circRNA expression profiles and the circRNA-microRNA(miRNA)-messenger RNA (mRNA) regulatory network in rheumatic heart disease (RHD) remain poorly understood. This study aimed to investigate the expressio...

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Bibliographic Details
Main Authors: Xiaoliang Chen, Lina Chen, Li Bi, Shunying Zhao, Xiaoyan Hu, Ni Li, Linwen Zhu, Guofeng Shao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
circular RNA
rheumatic heart diseases
regulatory network
diagnosis
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1639767/full
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https://www.frontiersin.org/articles/10.3389/fcvm.2025.1639767/full

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