The role and underlying mechanism of dental pulp stem cell-derived exosomal miR-31 in the treatment of osteoarthritis by targeting mTOR to enhance chondrocyte autophagy levels

The role and underlying mechanism of dental pulp stem cell-derived exosomal miR-31 in the treatment of osteoarthritis by targeting mTOR to enhance chondrocyte autophagy levels

Introduction Osteoarthritis is the most prevalent progressive musculoskeletal disease. It leads to functional impairment and decreased quality of life. However, the current treatments remain unsatisfactory. Recent studies have revealed that exosomes derived from mesenchymal stem cells offer a promis...

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Bibliographic Details
Main Authors: Guanglei Zhao, Jinyang Lyu, Xin Huang, Gangyong Huang, Feiyan Chen, Yibing Wei, Siqun Wang, Jun Xia, Jie Chen, Jingsheng Shi
Format: Article
Language:English
Published: Termedia Publishing House 2023-01-01
Series:Archives of Medical Science
Subjects:
exosome
dental pulp
osteoarthritis
stem cells
mtor
autophagy
Online Access:https://www.archivesofmedicalscience.com/The-role-and-underlying-mechanism-of-dental-pulp-stem-cell-derived-exosomal-miR-31,157032,0,2.html
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