Risk Factors Predicting Recurrent Small Intestinal Resection for Crohn’s Disease of the Terminal Ileum
This study examined potential risk factors for recurrent small intestinal resection in a ‘reagent-grade’ group of 94 consecutive patients with prior removal of histologically defined Crohn’s disease localized to the distal ileum seen by one gastroenterologist at a single teaching hospital. There wer...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
1994-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1994/241904 |
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| _version_ | 1832545485313802240 |
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| author | Hanna Binder Hugh J Freeman |
| author_facet | Hanna Binder Hugh J Freeman |
| author_sort | Hanna Binder |
| collection | DOAJ |
| description | This study examined potential risk factors for recurrent small intestinal resection in a ‘reagent-grade’ group of 94 consecutive patients with prior removal of histologically defined Crohn’s disease localized to the distal ileum seen by one gastroenterologist at a single teaching hospital. There were 38 males and 56 females ranging in age from 15 to 58 years, with an average length of follow-up of 8.7 years. Of these, 26% required a second resection for recurrent small intestinal disease. Cumulative reoperation rates in these 25 patients were 18% at five years and 24% at 10 years. Univariate and multivariate analyses of multiple demographic, clinical, laboratory and pathological variables revealed two apparent statistically significant independent risk factors for a second intestinal resection: steroid treatment, likely an indirect indication of more severe disease activity; and the presence of an internal fistula, consistent with the emerging concept of a relatively more aggressive clinical form of Crohn’s disease. |
| format | Article |
| id | doaj-art-117008cadc574cc9a76919e7e3d4e9cc |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 1994-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-117008cadc574cc9a76919e7e3d4e9cc2025-02-03T07:25:41ZengWileyCanadian Journal of Gastroenterology0835-79001994-01-018319319810.1155/1994/241904Risk Factors Predicting Recurrent Small Intestinal Resection for Crohn’s Disease of the Terminal IleumHanna Binder0Hugh J Freeman1Department of Medicine ( Gastroenterology), University of British Columbia and University Hospital, Vancouver, British Columbia, CanadaDepartment of Medicine ( Gastroenterology), University of British Columbia and University Hospital, Vancouver, British Columbia, CanadaThis study examined potential risk factors for recurrent small intestinal resection in a ‘reagent-grade’ group of 94 consecutive patients with prior removal of histologically defined Crohn’s disease localized to the distal ileum seen by one gastroenterologist at a single teaching hospital. There were 38 males and 56 females ranging in age from 15 to 58 years, with an average length of follow-up of 8.7 years. Of these, 26% required a second resection for recurrent small intestinal disease. Cumulative reoperation rates in these 25 patients were 18% at five years and 24% at 10 years. Univariate and multivariate analyses of multiple demographic, clinical, laboratory and pathological variables revealed two apparent statistically significant independent risk factors for a second intestinal resection: steroid treatment, likely an indirect indication of more severe disease activity; and the presence of an internal fistula, consistent with the emerging concept of a relatively more aggressive clinical form of Crohn’s disease.http://dx.doi.org/10.1155/1994/241904 |
| spellingShingle | Hanna Binder Hugh J Freeman Risk Factors Predicting Recurrent Small Intestinal Resection for Crohn’s Disease of the Terminal Ileum Canadian Journal of Gastroenterology |
| title | Risk Factors Predicting Recurrent Small Intestinal Resection for Crohn’s Disease of the Terminal Ileum |
| title_full | Risk Factors Predicting Recurrent Small Intestinal Resection for Crohn’s Disease of the Terminal Ileum |
| title_fullStr | Risk Factors Predicting Recurrent Small Intestinal Resection for Crohn’s Disease of the Terminal Ileum |
| title_full_unstemmed | Risk Factors Predicting Recurrent Small Intestinal Resection for Crohn’s Disease of the Terminal Ileum |
| title_short | Risk Factors Predicting Recurrent Small Intestinal Resection for Crohn’s Disease of the Terminal Ileum |
| title_sort | risk factors predicting recurrent small intestinal resection for crohn s disease of the terminal ileum |
| url | http://dx.doi.org/10.1155/1994/241904 |
| work_keys_str_mv | AT hannabinder riskfactorspredictingrecurrentsmallintestinalresectionforcrohnsdiseaseoftheterminalileum AT hughjfreeman riskfactorspredictingrecurrentsmallintestinalresectionforcrohnsdiseaseoftheterminalileum |