Proteomic analysis of infiltrating neutrophils from rheumatoid arthritis synovial fluid and their contribution to protein carbamylation

Proteomic analysis of infiltrating neutrophils from rheumatoid arthritis synovial fluid and their contribution to protein carbamylation

IntroductionCarbamylated proteins and dysregulated neutrophils are implicated in rheumatoid arthritis (RA) pathogenesis. Herein, we characterized the neutrophils present in RA synovial fluid (SF) using proteomic techniques and evaluated their contribution to protein carbamylation.MethodsRA-SF neutro...

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Bibliographic Details
Main Authors: Xueting Chen, Rong Du, Pan Wang, WenLin Qiu, Lu Chen, Jian Wan, Hui Qiu, Li Xiong, Kutty Selva Nandakumar, Rikard Holmdahl, Hui Geng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
Subjects:
carbamylation
myeloperoxidase
neutrophil
synovial fluid
rheumatoid arthritis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1563426/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1563426/full

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