The role of MCT1 in tumor progression and targeted therapy: a comprehensive review

Overexpression of monocarboxylate transporter 1 (MCT1) in tumor cells is often associated with poor prognosis. The established mechanisms through which MCT1 and its mediated lactate transport drive tumor progression are manifold. The classical mechanisms include fostering metabolic symbiosis among t...

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Bibliographic Details
Main Authors: Zheng Xu, Xuemei Wang, Hongjing Cheng, Jiuling Li, Xin Zhang, Xueju Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1610466/full
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