Current insights and future directions in systemic therapies for gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) in children and adolescents: a critical review of advancements and challenges

Current insights and future directions in systemic therapies for gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) in children and adolescents: a critical review of advancements and challenges

Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) in children and adolescents are rare and biologically heterogeneous. Due to their low incidence, therapeutic strategies are largely adapted from adult protocols, underscoring a critical need for paediatric-specific evidence.Surgical resectio...

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Bibliographic Details
Main Authors: Michaela Kuhlen, Katharina Karges, Marina Kunstreich, Maximilian Schmutz, Antje Redlich, Rainer Claus, Constantin Lapa
Format: Article
Language:English
Published: Elsevier 2025-12-01
Series:EJC Paediatric Oncology
Subjects:
Gastroenteropancreatic Neuroendocrine Neoplasms
Children and adolescents
Systemic therapies
Peptide receptor radionuclide therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2772610X25001072
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